Ocular Therapeutix - PharmaKB

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Company ReportsOcular Therapeutix

Ocular Therapeutix(OCUL)

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Dextenza	Dexamethasone	2018-11-30	2023-2039	Leukemia , Septic shock , Ulcerative colitis , Ankylosing spondylitis , Macular edema , Vomiting , Nausea , Uveitis , Sarcoidosis , Thrombocytopenic purpura idiopathic , Pulmonary tuberculosis , Mycosis fungoides , Systemic lupus erythematosus , Rheumatic diseases , Bursitis , Keratitis , Allergic rhinitis perennial , Thyroiditis , Iritis , Hypercalcemia , Brain edema , Pemphigus , Addison disease , Collagen diseases , Dermatitis herpetiformis , Wounds and injuries , Gastrointestinal diseases , Bacterial infections , Pseudomonas infections , Bacterial skin diseases , Skin diseases , Escherichia coli infections , Soft tissue infections , Bacterial eye infections , Urinary bladder diseases , Hepatic encephalopathy , Bacterial meningitis , Bacteremia , Klebsiella infections , Otitis externa , Haemophilus infections , Respiratory tract infections , Urinary tract infections , Intraabdominal infections , Infectious skin diseases , Staphylococcal infections , Central nervous system infections , Infectious bone diseases , Neutropenia , Prostatitis , Fever , Sinusitis , Typhoid fever , Diarrhea , Gonorrhea , Osteomyelitis , Campylobacter infections , Bacterial conjunctivitis , Infectious arthritis , Pyelonephritis , Proteus infections , Anthrax , Protozoan infections , Cystitis , Dysentery , Bacteroides infections , Pain , Ventricular tachycardia , Cardiac arrhythmias , Burns , Esophageal diseases , Ventricular fibrillation , Ventricular premature complexes , Mouth diseases , Paroxysmal tachycardia

Clinical Trials

Therapeutic Areas:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Dexamethasone sodium phosphate

,

dry eye syndromes

,

keratoconjunctivitis sicca

,

,

allergic conjunctivitis

,

corneal wavefront aberration

,

ocular hypertension

,

,

meibomian gland dysfunction

pancreatic neoplasms

,

hereditary sensory and autonomic neuropathies

,

essential thrombocythemia

,

polycythemia vera

,

primary myelofibrosis

,

,

,

diabetic nephropathies

,

kidney diseases

,

atopic dermatitis

,

,

alopecia areata

,

Calcium dobesilate

,

hematologic neoplasms

,

non-hodgkin lymphoma

,

,

hodgkin disease

healthy volunteers/patients

,

gastrointestinal neoplasms

,

follicular lymphoma

,

,

pancreatic neoplasms

,

neoplasm metastasis

,

respiratory tract diseases

,

pleural effusion

,

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

thoracic neoplasms

,

neoplasms by site

,

malignant pleural effusion

,

pleural diseases

,

pleural neoplasms

,

myeloid leukemia acute

,

,

squamous cell carcinoma of head and neck

,

head and neck neoplasms

,

,

squamous cell carcinoma

,

squamous cell neoplasms

,

multiple myeloma

,

chronic hepatitis c

,

,

,

adenocarcinoma of lung

,

non-small-cell lung carcinoma

,

type 2 diabetes mellitus

,

,

colorectal neoplasms

,

diabetes mellitus

,

,

non-hodgkin lymphoma

,

,

breast neoplasms

,

,

,

ischemic stroke

,

pulmonary embolism

,

,

papulosquamous skin diseases

,

essential hypertension

,

restless legs syndrome

,

,

rheumatoid arthritis

,

respiratory distress syndrome

,

vascular access devices

,

catheter obstruction

,

,

,

type 1 diabetes mellitus

,

,

polycystic kidney diseases

,

,

myocardial infarction

,

,

,

kidney diseases

,

diabetic neuropathies

,

diabetic nephropathies

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

liver cirrhosis

,

parkinson disease

,

peripheral arterial disease

,

intermittent claudication

,

peripheral vascular diseases

,

,

disease progression

,

hypersensitivity

,

extrinsic allergic alveolitis

non-small-cell lung carcinoma

,

hepatocellular carcinoma

,

liver neoplasms

,

renal cell carcinoma

,

breast neoplasms

,

triple negative breast neoplasms

,

,

colorectal neoplasms

,

neoplasm metastasis

,

,

malignant mesothelioma

Globulin, immune

healthy volunteers/patients

,

myeloid leukemia

,

head and neck neoplasms

,

myelodysplastic syndromes

,

,

uveal neoplasms

,

cutaneous malignant melanoma

,

,

endometrial neoplasms

,

,

,

multiple myeloma

,

mantle-cell lymphoma

,

,

esophageal neoplasms

,

,

,

biliary tract neoplasms

,

plasma cell neoplasms

,

choroidal neovascularization

,

,

waldenstrom macroglobulinemia

,

b-cell lymphoma marginal zone

,

aids-related lymphoma

,

bronchiolitis obliterans syndrome

,

unknown primary neoplasms

,

genomic instability

,

type 1 diabetes mellitus

,

cholangiocarcinoma

,

meningeal carcinomatosis

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

vascular graft occlusion

,

margins of excision

,

,

hemolytic-uremic syndrome

,

thrombotic thrombocytopenic purpura

,

thrombocytopenic purpura

,

,

,

behcet syndrome

,

extranodal nk-t-cell lymphoma

,

hereditary sensory and autonomic neuropathies

,

graft vs host disease

,

castleman disease

,

,

systemic lupus erythematosus

,

sjogren's syndrome

,

diabetic nephropathies

,

,

renal hypertension

,

diabetes mellitus

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

central nervous system neoplasms

,

nervous system neoplasms

,

pathologic neovascularization

,

burkitt lymphoma

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

sex cord-gonadal stromal tumors

,

interstitial lung diseases

,

erythema multiforme

,

reactive arthritis

,

immunoblastic lymphadenopathy

,

,

myasthenia gravis

,

neuroendocrine carcinoma

,

cytokine release syndrome

,

,

thoracic neoplasms

,

,

large b-cell lymphoma diffuse

,

liver neoplasms

,

b-cell lymphoma

,

follicular lymphoma

,

hepatocellular carcinoma

,

rectal neoplasms

,

triple negative breast neoplasms

,

,

renal cell carcinoma

,

neoplasm metastasis

,

macular degeneration

,

,

,

pancreatic neoplasms

,

,

,

small cell lung carcinoma

,

colonic neoplasms

,

ovarian epithelial carcinoma

,

urinary bladder neoplasms

,

,

esophageal squamous cell carcinoma

,

uterine cervical neoplasms

,

urologic neoplasms

,

transitional cell carcinoma

,

inflammatory breast neoplasms

,

ulcerative colitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

brain neoplasms

,

myeloid leukemia acute

,

prostatic neoplasms

,

thrombocytopenic purpura idiopathic

,

,

circulating neoplastic cells

,

malignant mesothelioma

,

diabetic retinopathy

,

multiple sclerosis

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

hematologic neoplasms

,

,

,

iga glomerulonephritis

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

castration-resistant prostatic neoplasms

,

retinal diseases

,

vision disorders

,

,

,

chronic progressive multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

neuromyelitis optica

,

myelin oligodendrocyte glycoprotein antibody-associated disease

,

guillain-barre syndrome

,

patient preference

,

lymphoproliferative disorders

,

neoplasms by histologic type

,

neoplasms by site

,

salivary gland neoplasms

,

,

gallbladder neoplasms

,

,

systemic vasculitis

,

disability evaluation

,

cognition disorders

,

,

hemolytic anemia autoimmune

,

malignant pleural effusion

,

nephrotic syndrome

,

focal segmental glomerulosclerosis

,

lipoid nephrosis

,

ankylosing spondylitis

,

retinal neovascularization

,

membranous glomerulonephritis

,

breast neoplasms

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

,

rheumatoid arthritis

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

,

lymphoid leukemia

,

ovarian neoplasms

,

stomach neoplasms

,

kidney transplantation

,

chronic kidney failure

,

granulomatosis with polyangiitis

,

,

microscopic polyangiitis

,

fallopian tube neoplasms

,

heart transplantation

,

kidney diseases

,

peritoneal neoplasms

,

pulmonary fibrosis

,

immunosuppression therapy

,

graft rejection

,

,

transplantation

,

renal insufficiency

,

food hypersensitivity

,

,

,

,

,

adenocarcinoma of lung

,

,

retinal vein occlusion

,

,

antiphospholipid syndrome

,

,

,

severe acute respiratory syndrome

,

communicable diseases

,

,

,

acquired immunodeficiency syndrome

,

neoadjuvant therapy

,

molecular targeted therapy

,

liver cirrhosis

,

atopic dermatitis

,

non-hodgkin lymphoma

,

multiple myeloma

,

renal cell carcinoma

Bos taurus adrenal cortex corticosteroids

,

,

hemostatic techniques

,

giant cell arteritis

,

polymyalgia rheumatica

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

b-cell chronic lymphocytic leukemia

,

breast neoplasms

,

,

,

animal mammary neoplasms

,

lymphoid leukemia

,

,

graft vs host disease

,

bronchiolitis obliterans syndrome

,

lupus nephritis

,

,

peritoneal neoplasms

,

intestinal obstruction

,

intermediate uveitis

,

,

follicular lymphoma

,

prostatic neoplasms

,

kidney transplantation

,

liver transplantation

,

chronic kidney failure

,

,

,

healthy volunteers/patients

,

chronic renal insufficiency

,

kidney diseases

,

,

renal replacement therapy

,

renal insufficiency

,

liver cirrhosis

,

drug-related side effects and adverse reactions

,

cytomegalovirus infections

,

communicable diseases

,

multiple sclerosis

,

,

relapsing-remitting multiple sclerosis

,

,

heart transplantation

,

,

,

,

cataract extraction

,

capsule opacification

healthy volunteers/patients

,

,

,

bacterial pneumonia

,

wounds and injuries

,

infectious skin diseases

,

,

community-acquired pneumonia

,

community-acquired infections

,

soft tissue infections

Fluoroquinolone

healthy volunteers/patients

,

diabetes mellitus

,

pharmacokinetics

,

major depressive disorder

,

,

long qt syndrome

,

alzheimer disease

,

,

chronic obstructive pulmonary disease

,

,

respiration disorders

,

,

,

rheumatoid arthritis

,

non-alcoholic fatty liver disease

,

alcoholic fatty liver

,

,

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